Acetylcholinesterase inhibitors from plants and fungi
Top Cited Papers
- 1 February 2006
- journal article
- review article
- Published by Royal Society of Chemistry (RSC) in Natural Product Reports
- Vol. 23 (2) , 181-199
- https://doi.org/10.1039/b508966m
Abstract
Covering: January 1980 to August 2005 This review describes 183 compounds obtained from plants and fungi which have been shown to inhibit acetylcholinesterase. The mechanism of action of cholinesterase, together with the binding sites, and, where this is known, the mode of action of inhibitors is described. The relative activities of the different compounds are recorded. The strongest inhibitors are generally alkaloids although some meroterpenoids from fungi have also been found to be active and display better selectivity.Keywords
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