Microsomal Esterification of Retinol in Human Liver
- 12 January 1984
- journal article
- research article
- Published by Wiley in Acta Medica Scandinavica
- Vol. 216 (4) , 403-407
- https://doi.org/10.1111/j.0954-6820.1984.tb03824.x
Abstract
Recent work has shown that esterification of retinol in microsomes from rat liver, mammary gland and small intestine and from human small intestine is catalyzed by an acyl CoA:retinol acyl transferase (ARAT). The present study demonstrates ARAT activity in human liver microsomes. At optimal incubation conditions the rate of retinyl ester formation due to ARAT (0.37 .+-. 0.31 nmol ester formed .cntdot. mg microsomal protein-1 min-1, n = 6) suggests that the enzyme is of physiological importance.Keywords
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