THE GORDON TEST FOR HODGKIN'S DISEASE

Publisher Website
Google Scholar
Abstract
In 1932 Gordon1reported the observation of a meningoencephalitic syndrome following the intracerebral inoculation of rabbits and guinea-pigs with a sterile suspension prepared from lymph nodes of typical Hodgkin's disease and in the ensuing year2suggested this procedure as a valuable diagnostic aid. Van Rooyen3and other English investigators4have corroborated this work and have affirmed the specificity of this test. From the reports in the literature (summarized in the accompanying table) the test has been applied in seventy-seven cases of Hodgkin's disease and has been found positive in fifty-six instances (77.9 per cent). Of 101 controls, consisting of normal lymph nodes and nodes showing carcinoma, sarcoma, lymphosarcoma, "pseudoleukemia," leukemia, tuberculosis, lymphoid hyperplasia and adenitis, the test was negative in ninetyeight cases (97 per cent), the three positive tests having been reported recently by Manson,5two of which were cases of tuberculous lymphadenitis and one

This publication has 0 references indexed in Scilit: