Positive Regulation of Wee1 by Chk1 and 14-3-3 Proteins
- 1 March 2001
- journal article
- Published by American Society for Cell Biology (ASCB) in Molecular Biology of the Cell
- Vol. 12 (3) , 551-563
- https://doi.org/10.1091/mbc.12.3.551
Abstract
Wee1 inactivates the Cdc2–cyclin B complex during interphase by phosphorylating Cdc2 on Tyr-15. The activity of Wee1 is highly regulated during the cell cycle. In frog egg extracts, it has been est...Keywords
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