Methoxamine Hydrochloride in the Treatment of Paroxysmal Supraventricular Tachycardia

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Abstract
Recent reports1 , 2 in the literature have suggested that methoxamine (beta-[2.5-dimethoxyphenyl] beta-hydroxyisopropylamine) chloride,¶ a synthetic amine, is effective in terminating attacks of supraventricular tachycardia. To corroborate these observations, 3 cases are added to the 4 already reported. These 3 cases are of particular interest because continuous electrocardiograms were taken during the course of the attack during the administration of methoxamine hydrochloride. The electrocardiograms demonstrate a dramatic reversion of the paroxysmal to the normal rhythm in a matter of seconds. No attempt is made in this paper to compare the value of methoxamine hydrochloride with that of other established methods of treatment . . .

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