Effect of Monofluorophosphate on the Pathways followed by Cariogenic Agents

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Abstract
The purpose of this study was to investigate the ultra structural changes in human enamel – untreated and pre-treated with Na2FPO3 – after an artificial carious attack. With the scanning electronmicroscope the influence of local fluoride application on surface topography and on the caries lesions in cross-sections was investigated. The results show that in Na2FPO3 pre-treated specimen the prism core dissolved faster than the interprismatic areas. The experiments indicated forthermore that most likely FPO32–– ions influence both transport of ions in the lesion and in the surface layer; FPO32–– application caused a considerable ‘clogging’ of the interprismatic areas. A preparation method is outlined by which a detailed comparison of pre-treated and untreated enamel originally located less than 0.25 mm apart is possible.

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