Dosing angiotensin II blockers—beyond blood pressure

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Abstract
It has been well established that at least in proteinuric renal disease, progressive loss of renal function can be effectively diminished, or even prevented, by antihypertensive treatment. This principle has been exemplified by early studies of Danish diabetologists [1,2] who administered beta-blockers, hydralazine and diuretics to patients with type 1 diabetes and nephropathy. The beneficial effect of lowering blood pressure has also been well established in non-diabetic renal disease [3].