Allosterism at Muscarinic Receptors: Ligands and Mechanisms
- 1 June 2005
- journal article
- review article
- Published by Bentham Science Publishers Ltd. in Mini-Reviews in Medicinal Chemistry
- Vol. 5 (6) , 523-543
- https://doi.org/10.2174/1389557054023251
Abstract
The evaluation of allosteric ligands at muscarinic receptors is discussed in terms of the ability of the experimental data to be interpreted by the allosteric ternary complex model. The compilation of useful SAR information of allosteric ligands is not simple, especially for muscarinic receptors, where there are multiple allosteric sites and complex interactions.Keywords
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