Biodistribution of rAAV Vectors Following Intraocular Administration: Evidence for the Presence and Persistence of Vector DNA in the Optic Nerve and in the Brain

This publication has 25 references indexed in Scilit:

• AAV-Mediated gene transfer slows photoreceptor loss in the RCS rat model of retinitis pigmentosa
  Molecular Therapy, 2003
• Recombinant adeno-associated virus serotype 4 mediates unique and exclusive long-term transduction of retinal pigmented epithelium in rat, dog, and nonhuman primate after subretinal delivery
  Published by Elsevier ,2003
• Intravitreal Gene Therapy Reduces Lysosomal Storage in Specific Areas of the CNS in Mucopolysaccharidosis VII Mice
  Journal of Neuroscience, 2003
• Functional and Structural Recovery of the Retina after Gene Therapy in the RPE65 Null Mutation Dog
  Investigative Opthalmology & Visual Science, 2003
• Immediate and Long-Term Safety of Recombinant Adeno-associated Virus Injection into the Nonhuman Primate Muscle
  Molecular Therapy, 2001
• Gene therapy restores vision in a canine model of childhood blindness
  Nature Genetics, 2001
• Restoration of photoreceptor ultrastructure and function in retinal degeneration slow mice by gene therapy
  Nature Genetics, 2000
• Reporter expression persists 1 year after adeno-associated virus-mediated gene transfer to the optic nerve.
  Archives of Ophthalmology (1950), 1999
• Persistent transgene product in retina, optic nerve and brain after intraocular injection of rAAV
  Vision Research, 1999
• Gene transfer into the mouse retina mediated by an adeno-associated viral vector
  Human Molecular Genetics, 1996