Changing approach to neonatal hepatitis and biliary atresia

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Abstract
Recently advanced ideas on the pathogenesis and interrelationships of neonatal hepatitis and biliary atresia, and on newer methods of surgical treatment of the latter, have generated renewed interest in the prognosis of these conditions, and in factors which influence it. In the past, those who believed that the operative curability of biliary atresia, by "conventional" enteric anastomoses, was very low (under 5% in most series), and who believed that surgical procedures, such as open liver biopsy and cholangiography employed to determine whether a patient had neonatal hepatitis or biliary atresia, significantly worsened the prognosis of neonatal hepatitis, could even wonder whether exploration of a patient who might have either disease was really warranted.

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