Cost of care for patients with rheumatoid arthritis receiving TNF-antagonist therapy using claims data
- 22 June 2007
- journal article
- Published by Informa Healthcare in Current Medical Research and Opinion
- Vol. 23 (8) , 1749-1759
- https://doi.org/10.1185/030079907x210615
Abstract
Objective: To compare the cost of care for rheumatoid arthritis (RA) patients treated with adalimumab, infliximab, and etanercept.Research design and methods: RA patients were identified from a privately insured database. Three mutually exclusive treatment cohorts were formed based on the date of first tumor necrosis factor (TNF) antagonist treatment (index date) after January 1, 2003. Baseline characteristics were assessed in the 3-month pretreatment period. Healthcare (i.e., medical service and prescription medications) utilization and cost were assessed for the following 12 months. RA-related medical cost included the total cost for medical service associated with RA diagnosis. RA-related healthcare cost included RA-related medical and drug cost. Uneven distribution of baseline characteristics were adjusted with the propensity score method. Cost was compared between treatment cohorts.Results: Twelve-month TNF-antagonist therapy cost ($12 853 vs. 17 299, p = 0.002), total RA-related drug cost (...Keywords
This publication has 7 references indexed in Scilit:
- Retrospective study of the costs of care during the first year of therapy with etanercept or infliximab among patients aged ≥65 years with rheumatoid arthritisClinical Therapeutics, 2005
- Frequency, Predictors, and Economic Impact of Upward Dose Adjustment of Infliximab in Managed Care Patients With Rheumatoid ArthritisJournal of Managed Care Pharmacy, 2005
- The role of the propensity score in estimating dose-response functionsBiometrika, 2000
- Direct and Indirect Costs of Rheumatoid Arthritis to an EmployerJournal of Occupational and Environmental Medicine, 2000
- Propensity score methods for bias reduction in the comparison of a treatment to a non-randomized control groupStatistics in Medicine, 1998
- Special article the economic cost and social and psychological impact of musculoskeletal conditionsArthritis & Rheumatism, 1995
- A new method of classifying prognostic comorbidity in longitudinal studies: Development and validationJournal of Chronic Diseases, 1987