SILYL PHOSPHITES V. THE REACTIONS OF TRIS(TRIMETHYLSILYL) PHOSPHITE WITH CARBONYL COMPOUNDS
- 5 May 1977
- journal article
- research article
- Published by Oxford University Press (OUP) in Chemistry Letters
- Vol. 6 (5) , 485-488
- https://doi.org/10.1246/cl.1977.485
Abstract
When tris(trimethylsilyl) phosphite (1) was treated with aldehydes, ketones, or α,β-unsaturated aldehydes at room temperature, the 1,2-adducts were obtained in high yields (75–94%). On the other hand, when α,β-unsaturated ketones or ethyl crotonate was used, the 1,4-adducts were obtained in high yields (71–84%). The silylated products were smoothly hydrolyzed to the corresponding phosphonates in almost quantitative yields by addition of alcohol or water.Keywords
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