Ventricular fibrillation thresholds in the presence of leakage currents

Abstract
Experiments were performed on young healthy dogs anaesthetized with a mixture of nitrous oxide and halothane. A fluid-filled catheter was introduced into the right ventricle of these animals and a 60 Hz electrical current was caused to flow down the catheter. It was found that complete loss of organized ventricular contractions and consequent fall in arterial pressure occurred at a current of less than 20 μA in a significant number of cases and was five times lower than that needed to cause sustained ventricular fibrillation.

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