RENAL-FUNCTION AFTER THERMAL TRAUMA - EFFECTS OF TREATMENT ON RENAL BLOOD-FLOW AND SODIUM AND WATER EXCRETION

  • 1 January 1976
    • journal article
    • research article
    • Vol. 79  (3) , 342-345
Abstract
Effective renal plasma flow, urine Na excretion and glomerular filtration rates were reduced markedly to 44%, 46%, and 60% of normal, respectively, in rats subjected to thermal trauma. A Na load of about 2 meq/100 g of body weight restores these functions toward normal. Doubling the concomitant water load had no discernible beneficial effect, but rats resuscitated with the larger water load were in greater positive water balance. The water loads commonly administered clinically for the treatment of burn shock may be unnecessarily large.

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