A nucleotide change in the anticodon of anEscherichia coliserine transfer RNA results InsupD–amber suppression
- 1 January 1983
- journal article
- Published by Oxford University Press (OUP) in Nucleic Acids Research
- Vol. 11 (11) , 3823-3832
- https://doi.org/10.1093/nar/11.11.3823
Abstract
The tRNAs specified by the wild type and amber suppressor alleles of the Escherichia coli supD gene have been identified, and their primary structures determined. The sequences differ by a single nucleotide in the middle of the anticodon. A CUA anticodon allows the suppressor tRNA to read the UAG stop codon; the CGA anticodon in the minor serine tRNA species from which the suppressor is derived is specific for the serine codon UCG.Keywords
This publication has 31 references indexed in Scilit:
- Nucleotide alterations in bacteriophage T4 serine transfer RNA that affect the conversion of precursor RNA into transfer RNAJournal of Molecular Biology, 1975
- Escape synthesis of the biotin operon in induced λb2 lysogensJournal of Molecular Biology, 1972
- Prophage lambda at unusual chromosomal locations: I. Location of the secondary attachment sites and the properties of the lysogensJournal of Molecular Biology, 1972
- Tryptophan transfer RNA as the UGA suppressorJournal of Molecular Biology, 1971
- Studies on polynucleotidesJournal of Molecular Biology, 1968
- Studies on polynucleotidesJournal of Molecular Biology, 1967
- Suppressor genes for nonsense mutationsJournal of Molecular Biology, 1965
- Suppression in vitro: Identification of a Serine-sRNA as a "Nonsense" SuppressorScience, 1965
- Molecular consequences of the amber mutation and its suppressionJournal of Molecular Biology, 1965
- Mécanismes régulateurs dans la biosynthèse des enzymes du métabolisme du galactose chez Escherichia coli K12Journal of Molecular Biology, 1963