Shunting of prostanoid biosynthesis in microsomal prostaglandin E synthase‐1 null embryo fibroblasts: regulatory effects on inducible nitric oxide synthase expression and nitrite synthesis
Open Access
- 3 October 2006
- journal article
- fj express-summaries
- Published by Wiley in The FASEB Journal
- Vol. 20 (13) , 2387-2389
- https://doi.org/10.1096/fj.06-6366fje
Abstract
Microsomal postaglandin (PG) E synthase (mPGES)‐1 is an inducible enzyme that acts downstream of cyclooxygenase (COX) and specifically catalyzes the conversion of prostaglandin (PG)H2 to PGE2, most p...Keywords
This publication has 51 references indexed in Scilit:
- Atorvastatin Reduces the Expression of Prostaglandin E2 Receptors in Human Carotid Atherosclerotic Plaques and Monocytic CellsJournal of Cardiovascular Pharmacology, 2006
- Cardiovascular Events Associated with Rofecoxib in a Colorectal Adenoma Chemoprevention TrialNew England Journal of Medicine, 2005
- Cardiovascular Risk Associated with Celecoxib in a Clinical Trial for Colorectal Adenoma PreventionNew England Journal of Medicine, 2005
- Expression of microsomal prostaglandin E synthase 1 in rheumatoid arthritis synoviumArthritis & Rheumatism, 2004
- Cardiovascular thrombotic events in arthritis trials of the cyclooxygenase-2 inhibitor celecoxib**The investigators had full access to the data and complete control over the design, conduct analysis, interpretation, and description of the study. The sponsor of the study had no role in study design, data collection, data analysis, data interpretation, or in writing the report. The views expressed are those of the investigators alone.The American Journal of Cardiology, 2003
- Specific cyclooxygenase-2 inhibitors: what have we learned since they came into widespread clinical use?Current Opinion in Rheumatology, 2002
- Identification and Characterization of a Novel Type of Membrane-Associated Prostaglandin E SynthaseBiochemical and Biophysical Research Communications, 2002
- Endothelial function as a determinant of vascular function and structure: A new therapeutic targetThe American Journal of Cardiology, 1997
- Physiological and pathophysiological roles of nitric oxideMicrosurgery, 1994
- Arachidonic Acid Metabolites and the Interactions between Platelets and Blood-Vessel WallsNew England Journal of Medicine, 1979