Ragulator-Rag Complex Targets mTORC1 to the Lysosomal Surface and Is Necessary for Its Activation by Amino Acids
Top Cited Papers
- 1 April 2010
- Vol. 141 (2) , 290-303
- https://doi.org/10.1016/j.cell.2010.02.024
Abstract
No abstract availableKeywords
This publication has 37 references indexed in Scilit:
- mTOR signaling at a glanceJournal of Cell Science, 2009
- TORC2 Plasma Membrane Localization Is Essential for Cell Viability and Restricted to a Distinct DomainMolecular Biology of the Cell, 2009
- The novel lipid raft adaptor p18 controls endosome dynamics by anchoring the MEK–ERK pathway to late endosomesThe EMBO Journal, 2009
- The yeast lysosome-like vacuole: Endpoint and crossroadsPublished by Elsevier ,2008
- Regulation of TORC1 by Rag GTPases in nutrient responseNature Cell Biology, 2008
- The Rag GTPases Bind Raptor and Mediate Amino Acid Signaling to mTORC1Science, 2008
- p14–MP1-MEK1 signaling regulates endosomal traffic and cellular proliferation during tissue homeostasisThe Journal of cell biology, 2006
- A conserved GTPase-containing complex is required for intracellular sorting of the general amino-acid permease in yeastNature Cell Biology, 2006
- Novel Role of the Small GTPase Rheb: Its Implication in Endocytic Pathway Independent of the Activation of Mammalian Target of RapamycinThe Journal of Biochemistry, 2005
- Phosphorylation and Regulation of Akt/PKB by the Rictor-mTOR ComplexScience, 2005