A NEW SYNTHETIC METHOD FOR THE TRANSFORMATION OF ALCOHOLS TO ALKYL CHLORIDES USING 2-CHLOROBENZOXAZOLIUM SALT

5 April 1977

journal article
research article
Published by Oxford University Press (OUP) in Chemistry Letters

Vol. 6 (4) , 383-386
https://doi.org/10.1246/cl.1977.383

Abstract

2-Chloro-3-ethylbenzoxazolium tetrafluoroborate reacts smoothly with a variety of alcohols in the presence of tetraethylammonium chloride to afford the corresponding alkyl chlorides in high yields. Replacement of a hydroxyl group at an asymmetric carbon atom with chlorine proceeds in a stereospecific manner.

Keywords

ALCOHOLS
CHLORIDES USING
NEW SYNTHETIC
ALKYL CHLORIDES
CHLOROBENZOXAZOLIUM SALT
SYNTHETIC METHOD

This publication has 1 reference indexed in Scilit:

AZIDINIUMSALZE, I Synthese quasiaromatischer Azidocyclimonium‐fluoroborate
European Journal of Organic Chemistry, 1961