Abstract
Thirty-six albino rats were divided into 4 groups of 9 each. Two of these groups had stainless steel wire around the lower anterior teeth to act as an irritant to the gingiva. One group with the wire and 1 group without the wire received daily injections intraperitoneally of 1.0 mg of Dilantin Sodium for 90 dyas. The remaining rats were used as controls. No change in the gingiva was observed grossly or microscopically following the administration of this drug to rats.

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