Effect of Incubation on the Cholesterol Partition in Human Serum.
- 1 August 1949
- journal article
- research article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 71 (4) , 633-637
- https://doi.org/10.3181/00379727-71-17280
Abstract
Incubation of normal human serum and that of patients with disease not involving the liver results in a drop in free cholesterol of more than 30% without change in the total cholesterol. The reaction is probably due to an enzyme as the decrease does not occur when the serum is heated to 56[degree]C before incubation. In this small series the decrease in free cholesterol with incubation was usually less than normal with disease of the liver parenchyma and occasionally with extrahepatic obstructive jaundice. The decrease in free cholesterol apparently did not parallel changes in serum bili-rubin, alkaline phosphatase, serum albumin, or the cephalin flocculation test. There appeared to be some correlation with the percentage of cholesterol esters in the control serum.Keywords
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