• 1 January 1979
    • journal article
    • research article
    • Vol. 43  (4) , 380-383
Abstract
The concentrations of basophils in blood and bone marrow were monitored in guinea pigs subjected to primary and secondary infestations with larvae of Dermacentor andersoni. In these guinea pigs a significant increase of basophils was evident in peripheral blood. The response following the secondary infestation was more rapid and more intense than that following the primary infestation. Similar changes also occurred in bone marrow. The possible significance of these responses in relation to acquired tick resistance in guinea pigs is discussed.