ADRENAL SECRETION DURING ANAPHYLACTIC SHOCK

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Abstract
With the left lumbo-adrenal vein of 1 dog anastomosed to the jugular of a 2nd, blood pressure and heart rate of the vagotomized recipient, whose stellate ganglia had been excised, were used as an index of the donor''s adrenin secretion. Injection of 0.1-0.15 cc. of horse serum into the donor''s left adrenal gland produced no effect in the recipients. When the donor had been previously sensitized to horse serum, similar injections in 4 of 5 cases evidently produced a discharge of adrenin. When sensitized donor was shocked by intravenous injection of 1-4 cc. of horse serum, there was no effect in recipient until after 5 min., when a slight rise in blood pressure occurred in 4 of 5 cases, with concomitant cardio-acceleration in 2. This rise generally occurred while the donor''s blood pressure was returning to normal.

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