Asymmetric Addition Reaction to Non-Prochiral Carbonyl Compound: Asymmetric Catalytic Formaldehyde-Ene Reaction for Isocarbacyclin Synthesis
- 1 January 1995
- journal article
- letter
- Published by Georg Thieme Verlag KG in Synlett
- Vol. 1995 (01) , 29-31
- https://doi.org/10.1055/s-1995-4878
Abstract
Asymmetric catalysis of ene-type carbonyl addition to achiral/non-prochiral formaldehyde with the homotopic faces is described to provide a new route to the asymmetric synthesis of isocarbacyclin and 3-oxa analogues.Keywords
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