The kinetics of dissolution for a non-disintegrating standard substrate
- 1 August 1971
- journal article
- Published by Oxford University Press (OUP) in Journal of Pharmacy and Pharmacology
- Vol. 23 (8) , 573-582
- https://doi.org/10.1111/j.2042-7158.1971.tb08719.x
Abstract
The dissolution profiles for a 1 cm sodium chloride cube, which was considered to represent a standard non-distintegrating substrate, were obtained in seven kinds of dissolution apparatus. The results were used to assess experimental reproducibility and apparatus variables and to examine the adherence of the kinetics of the dissolution process to theoretical rate laws.Keywords
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