Reduced Leucine-Enkephalin—Like Immunoreactive Substance in Hamster Basal Ganglia After Long-Term Ethanol Exposure
- 25 June 1982
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 216 (4553) , 1425-1427
- https://doi.org/10.1126/science.7089531
Abstract
Golden Syrian hamsters were placed individually in cages with three drinking bottles--one empty, one containing water, and the third containing water and ethanol. Control hamsters received water only. After 1 year the experimental hamsters showed a significantly lower concentration of leucine-enkephalin-like immunoreactive substance in the basal ganglia than the control hamsters. This finding indicates that the action of ethanol involves endogenous peptidyl opiates.This publication has 26 references indexed in Scilit:
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