THE EFFECT OF GLUTEN ON HLA-DR IN THE SMALL INTESTINAL EPITHELIUM OF PATIENTS WITH CELIAC-DISEASE

  • 1 January 1986
    • journal article
    • research article
    • Vol. 63  (1) , 101-104
Abstract
Frozen sections of control and coeliac jejunal mucosa were examined for HLA-DR staining. In general the staining pattern in the controls and treated coeliac patients was a patchy subapical pattern on villous tips. Untreated coeliac patients gave a different pattern with staining extending to the crypt enterocytes. Gluten challenge in three treated coeliac patients induced an altered staining pattern within 2 h.