Hepatic artery embolization for inoperable hepatocellular carcinoma; prognosis and Risk Factors

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Abstract
During a 7-year period in our hospital, 69 patients with inoperable hepatocellular carcinoma (HCC) underwent 111 courses of transcatheter hepatic artery embolization (TAE) and/or chemoinfusion with lipiodol. Patient survival was 0.5–37 months following therapy and the factors affecting prognosis were evaluated. Survival rates at 1, 2 and 3 years after TAE were 53%, 24% and 15%, respectively. Survival rates at 1, 2 and 3 years in relation to tumor size were 100%, 100% and 100% in 5 patients (tumor size 5.1 cm). An analysis of prognostic factors showed that the size of the main tumor significantly influenced the prognosis following TAE (PP<0.1). These results suggest that TAE has a significant potential for becoming the first choice of treatment for patients with small multiple HCCs (<2 cm), provided that neither severe hepatic dysfunction nor a tumor thrombus in the main portal vein is present.