Increases in morphologically abnormal sperm in rats exposed to Co60 irradiation
- 1 January 1980
- journal article
- research article
- Published by Wiley in Environmental Mutagenesis
- Vol. 2 (2) , 125-131
- https://doi.org/10.1002/em.2860020204
Abstract
We have investigated the effects of testicular exposure to different doses of Co60 radiation on sperm morphology in F-344 rats. The results indicate that from 150rad to 500 rad gamma irradiation causes statistically significant, dose-related increases in 1) the percent of morphologically aberrant sperm and 2) the frequency of tailless sperm. Both of these effects were detectable in sperm which were derived from treated spermatid, spermatocytes, and spermatogonial cells. These data indicate that the development of a sperm morphology assay in rats is feasible.Keywords
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