Triazene drug metabolites: base catalysed formation of n-alkyltriazenes from n-hydroxymethyl-n-alkyltriazenes
- 1 January 1985
- journal article
- Published by Elsevier in Tetrahedron Letters
- Vol. 26 (12) , 1557-1560
- https://doi.org/10.1016/s0040-4039(00)98551-4
Abstract
No abstract availableKeywords
This publication has 6 references indexed in Scilit:
- Open-chain nitrogen compounds. Part V. Hydroxymethyltriazenes: synthesis of some new alkyl homologues of the anti-tumour 3-methyl-3-hydroxymethyltriazenes and preparation of the derived acetoxymethyl-, benzoyloxymethyl-, and methoxymethyltriazenesCanadian Journal of Chemistry, 1984
- Studies of the mode of action of antitumor triazenes and triazines. 6. 1-Aryl-3-(hydroxymethyl)-3-methyltriazenes: synthesis, chemistry, and antitumor propertiesJournal of Medicinal Chemistry, 1984
- Carbinolamines and related structures—Potential alkylating metabolites of clinically active anticancer drugsJournal of Theoretical Biology, 1983
- Biological properties of antitumor triazenesIndustrial & Engineering Chemistry Product Research and Development, 1981
- MonoalkyltriazenesChemical Society Reviews, 1978
- Equilibriums and kinetics of N-hydroxymethylamine formation from aromatic exocyclic amines and formaldehyde. Effects of nucleophilicity and catalyst strength upon mechanisms of catalysis of carbinolamine formationJournal of the American Chemical Society, 1976