Ein belastungsabhängiges pulsatiles Kreislaufmodell als Grundlage für die Regelung von Kunstherzen - A Load-dependent Pulsatile Circulation Model as the basis of Artificial Heart Control

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Abstract
The development and simulation of closed-loop control of blood pumps requires a pulsatile model of the cardiovascular system that takes into account the natural mechanisms of adaptation during exercise. In this article, a model is described which takes account of the baroreceptor reflex, the change in heart rate, contractility of the heart, and the peripheral resistance during exercise, as well as venous tone, and the nonlinearity of vessel compliance. In addition, a model of the artificial heart is presented, in which the nonlinear limitation of the stroke volume is taken into account, and the concept of a pulse frequency modulated (PFM) control system for the circulation with an artificial heart is described.

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