Effect of Propranolol on Arrhythmias following Coronary Artery Occlusion in Dogs
- 1 January 1967
- journal article
- research article
- Published by Oxford University Press (OUP) in Cardiovascular Research
- Vol. 1 (1) , 34-41
- https://doi.org/10.1093/cvr/1.1.34
Abstract
Electrocardiograms were obtained from conscious dogs before and on the four days after acute ligation of a branch of the left coronary artery. The intravenous injection of propranolol did not abolish the arrhythmias present 24 hr. after ligation, but reduced or abolished the exaggerated ectopic response to adrenaline on the second to fourth days after ligation. This effect resulted from blockade of adrenergic β-receptors in the myocardium.Keywords
This publication has 12 references indexed in Scilit:
- ANTISYMPATHOMIMETIC AND ANTIFIBRILLATORY EFFECTS OF PRONETHALOL AND PROPRANOLOLBritish Journal of Pharmacology and Chemotherapy, 1966
- COMPARISON OF SOME PROPERTIES OF PRONETHALOL AND PROPRANOLOLBritish Journal of Pharmacology and Chemotherapy, 1965
- Relationship Between Potassium and Vagal Action on Atrioventricular TransmissionCirculation Research, 1965
- Propranolol and ventricular arrhythmias with halothaneAnaesthesia, 1965
- Propranolol (Inderal) in Persistent Ventricular FibrillationBMJ, 1965
- Propranolol (Inderal) in Disturbances of Cardiac RhythmBMJ, 1965
- THE EFFECTS ON CARDIAC MUSCLE OF β‐RECEPTOR ANTAGONISTS IN RELATION TO THEIR ACTIVITY AS LOCAL ANAESTHETICSBritish Journal of Pharmacology and Chemotherapy, 1965
- Reduction by Hyperbaric Oxygenation of the Mortality from Ventricular Fibrillation Following Coronary Artery LigationCirculation Research, 1964
- HAeMODYNAMIC BASIS OF ACUTE PRESSOR REACTIONS AND HYPERTENSIONHeart, 1963
- Delayed Development of Ventricular Ectopic Rhythms following Experimental Coronary OcclusionCirculation, 1950