MONOCYTE/T-CELL INTERACTIONS IN CON A INDUCED SUPPRESSOR ACTIVITY

Abstract
The peripheral blood mononuclear cell (PBMC) content of monocytes and its impact on registered suppressor activity of human PBMC populations was examined. Monocytes were unnecessary for the concanavalin A (Con A) induction of PBMC, and monocytes exhibited no Con A dependent suppressor potential. The presence of monocytes was unnecessary for the Con A activated lymphocytes to exert their suppressor activity against the responder system, i.e., a Con A stimulated lymphoblast transformation.

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