Elevation of Plasma Bromide Levels in Patients Following Halothane Anesthesia
Open Access
- 1 March 1976
- journal article
- review article
- Published by Wolters Kluwer Health in Anesthesiology
- Vol. 44 (3) , 194-196
- https://doi.org/10.1097/00000542-197603000-00003
Abstract
Plasma bromide concentrations of 25 patients were determined before and after halothane anesthesia. A high correlation (r greater than .70) between exposure to halothane in MAC-hours and plasma bromide levels 24, 48 and 72 hours later was found. Peak bromide levels occurred 48-72 hours after anesthesia in 16 patients (64 per cent), and ranged from 52 mug/ml (0.65 mEq/l) to 180 mug/mo (2.25 mEq/l). Bromide levels remained elevated for prolonged periods (at least 22 days in some patients). Possible sedative or psychoactive effects of increased plasma bromide levels are discussed.Keywords
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