BCG and Cancer

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Abstract
CLINICAL evaluation of BCG for the treatment of cancer is under way in at least 50 centers throughout the world. Use of BCG in such cases has been encouraged by work with animal tumors indicating that BCG treatment can modify the action of carcinogens, prevent growth of tumor transplants and eliminate established tumors. In some reports BCG has not been effective or has even enhanced tumor growth. Sufficient data are now available to identify at least some of the factors that contribute to the success or failure of BCG immunotherapy.BCG was originally isolated by Calmette and Guérin at the . . .