The exclusion of patients from a clinical trial
- 1 January 1982
- journal article
- research article
- Published by Wiley in Statistics in Medicine
- Vol. 1 (3) , 261-265
- https://doi.org/10.1002/sim.4780010307
Abstract
In designing a clinical trial, the investigator must often decide whether or not to exclude certain patients from randomization. Using Bayesian analysis this paper proposes a criterion for making this decision, based on an extension of Colton's model for the choice between two medical treatments.Keywords
This publication has 9 references indexed in Scilit:
- Explanatory and pragmatic attitudes in therapeutical trialsPublished by Elsevier ,2004
- Null results in clinical trials: the need for a decision-theory approachBritish Journal of Cancer, 1980
- The design of a clinical trial with several patient categoriesThe Canadian Journal of Statistics / La Revue Canadienne de Statistique, 1979
- Design and analysis of randomized clinical trials requiring prolonged observation of each patient. I. Introduction and designBritish Journal of Cancer, 1976
- The design of a clinical trial when there are two categories of patientsThe Canadian Journal of Statistics / La Revue Canadienne de Statistique, 1976
- A note comparing three measures of subjective probability, their validity and reliabilityActa Psychologica, 1974
- Intrasubject comparison of four response modes for “subjective probability” assessmentOrganizational Behavior and Human Performance, 1973
- Report of a symposium sponsored by the UICC on principles and practice in clinical trialsInternational Journal of Cancer, 1971
- A Model for Selecting One of Two Medical TreatmentsJournal of the American Statistical Association, 1963