The Gene Balance Hypothesis: From Classical Genetics to Modern Genomics
Top Cited Papers
Open Access
- 9 February 2007
- journal article
- review article
- Published by Oxford University Press (OUP) in Plant Cell
- Vol. 19 (2) , 395-402
- https://doi.org/10.1105/tpc.106.049338
Abstract
The concept of genetic balance traces back to the early days of genetics. Additions or subtractions of single chromosomes to the karyotype (aneuploidy) produced greater impacts on the phenotype than whole-genome changes (ploidy). Studies on changes in gene expression in aneuploid and ploidy seriesKeywords
This publication has 51 references indexed in Scilit:
- Global variation in copy number in the human genomeNature, 2006
- Global trends of whole-genome duplications revealed by the ciliate Paramecium tetraureliaNature, 2006
- Following tetraploidy in an Arabidopsis ancestor, genes were removed preferentially from one homeolog leaving clusters enriched in dose-sensitive genesGenome Research, 2006
- Gene dosage balance: deletions, duplications and dominanceTrends in Genetics, 2005
- Regulatory evolution across the protein interaction networkNature Genetics, 2004
- Gene Dosage Balance in Cellular PathwaysGenetics, 2004
- Dosage sensitivity and the evolution of gene families in yeastNature, 2003
- A bZIP protein, sisterless-a, collaborates with bHLH transcription factors early in Drosophila development to determine sex.Genes & Development, 1993
- Nullisomic Analysis in Common WheatThe American Naturalist, 1953
- VorbemerkungMolecular Genetics and Genomics, 1920