Genotype Distributions in Top-level Soccer Players: A Role forACE?
- 10 March 2009
- journal article
- research article
- Published by Georg Thieme Verlag KG in International Journal of Sports Medicine
- Vol. 30 (05) , 387-392
- https://doi.org/10.1055/s-0028-1105931
Abstract
We determined the genotype and allelic frequency of several genetic polymorphisms (ACE I/D, GDF-8 K153R [and also E164 K, P198A and I225 T] and AMPD1 C34 T) that are candidates to influence sports performance in a group of 54 male professional soccer players. Their results were compared with those of elite endurance male athletes (52 runners) and 123 sedentary, healthy men (controls). We found statistical significance for the ACE ID (χ2 (2)=8.176, P=0.017) and II genotypes (χ2 (2)=16.137, PP=0.005) and II (PAMPD1 (with a higher frequency of the CT genotype in soccer players than in runners [χ2 (2)=7.538, P=0.006]) but not for GDF-8 K153R. Since the ACE II genotype is associated with improved potential for endurance performance but with decreased training gains in muscle mass and strength, these findings together with previous results [ 37 ] support the notion that elite soccer players tend to have a power/strength oriented genotype.Keywords
This publication has 0 references indexed in Scilit: