(2S,3R)-2-Benzyloxy-3,4-epoxybutan-1-ol, A Versatile Synthetic Building Block Formally Derived From (u)-Tartaric acid
- 1 May 1988
- journal article
- research article
- Published by Georg Thieme Verlag KG in Synthesis
- Vol. 1988 (05) , 373-375
- https://doi.org/10.1055/s-1988-27577
Abstract
The title chiral C4-building block2 1, a meso-tartaric acid synthon, is prepared from dimethyl (R,R)-O,O′-benzylidenetartrate on a multigram scale. The key step is a tosylation- reduction sequence which leads to the diol 5.Keywords
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