PERORAL XYLITOL INCREASES INTESTINAL CALCIUM-ABSORPTION IN THE RAT INDEPENDENTLY OF VITAMIN-D ACTION

  • 1 January 1985
    • journal article
    • research article
    • Vol. 11  (3) , 178-181
Abstract
The absorption of 45Ca from the diet in the presence of xylitol was investigated with 28 adult male rats. The supplementation of the diet with 10% xylitol for 3 wk augmented the urinary excretion of 45Ca 2.5-fold (P < 0.001), but did not affect the urinary excretion of Na. The concentration of Ca in the serum remained unchanged. The serum levels of vitamin D metabolites [1,25-(OH)2D; 24,25-(OH)2D and 25-(OH)D] did not correlate with the augmentation of Ca absorption. The diuretic effect of xylitol and the complex formation between polyols and Ca in rat intestine were considered responsible for the changes in Ca metabolism.

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