Association of Life Activities With Cerebral Blood Flow in Alzheimer Disease

Abstract
THE COGNITIVE reserve (CR) hypothesis suggests that there are individual differences in the ability to cope with the pathologic changes in Alzheimer disease (AD).1 Innate intelligence or aspects of life experience may supply reserve in the form of a set of skills or repertoires that allow some people to cope with the pathologic changes better than others. Educational and occupational attainments are considered such aspects of life experience.