FURTHER TEST OF POSSIBLE CORRELATION BETWEEN CROSS- LINKING AND CHROMOSOME BREAKING ABILITIES OF CHEMICAL MUTAGENS

1 January 1964

journal article
research article
Published by Genetics Society of Japan in The Japanese Journal of Genetics

Vol. 39 (2-3) , 155-163
https://doi.org/10.1266/jjg.39.155

Abstract

The frequencies of sex-linked lethals and translocations were determined in the progeny of Drosophila injected with either ethylene imine or 2:4; 6-tri (ethyleneimino)-l:3:5-triazine (TEM). The ratio of translocations to lethals was the smallest in the case of TEM-treatment. TEM did in fact induce fewer translocations that expected from the number of functional arms. It was concluded that the alkylating substances with polyfunctional arms are not more efficient in producing chromosome breakage than those with monofunc-tional arm.

This publication has 4 references indexed in Scilit:

Sensitivity of the Drosophila testis to tri-ethylene melamine (TEM)
Genetics Research, 1961
THE REACTIONS OF THE “RADIOMIMETIC” ALKYLATING AGENTS WITH MACROMOLECULES IN VITRO
Annals of the New York Academy of Sciences, 1958
PROBLEMS IN CHEMICAL MUTAGENESIS
Cold Spring Harbor Symposia on Quantitative Biology, 1951
The Chemical Production of Mutations
Science, 1947