INTERMEDIARY METABOLISM OF CLOSTRIDIUM ACIDI-URICI I

Abstract
Freshly prepared, cell-free extracts of C. acidi-urici form pyruvate from glycine and formaldehyde. Treatment with Dowex-1-chloride inactivates the extracts. Of several folic acid-like compounds tested, only tetrahydrofolic acid was able to restore activity to the extracts. It is suggested that glycine and formaldehyde are converted to pyruvate via L-serine.