Release of Metaraminol (Aramine) from the Heart by Sympathetic Nerve Stimulation
- 21 August 1964
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 145 (3634) , 828-829
- https://doi.org/10.1126/science.145.3634.828
Abstract
Cats were injected intravenously with metaraminol, an amine which depletes norepinephrine from the sympathetic nerve endings; their hearts were then perfused in vitro. Stimulation of the sympathetic nerve supply released metaraminol from the hearts, demonstrating that a synthetic compound can replace norepinephrine and serve as a transmitter at adrenergic nerve endingsKeywords
This publication has 10 references indexed in Scilit:
- Release by sympathetic stimulation of α-methylnoradrenaline stored in the heart after administration of α-methyldopaCellular and Molecular Life Sciences, 1963
- Studies on the Mechanism of Action of Metaraminol (Aramine)Annals of Internal Medicine, 1963
- STUDIES ON DISTRIBUTION OF EXOGENOUS NOREPINEPHRINE IN SYMPATHETIC NEUROTRANSMITTER STORE1963
- ON THE MECHANISM OF TACHYPHYLAXIS TO TYRAMINE IN THE ISOLATED RAT HEARTBritish Journal of Pharmacology and Chemotherapy, 1962
- Release of Norepinephrine from the Heart by Vasoactive AminesExperimental Biology and Medicine, 1962
- MECHANISM OF NOREPINEPHRINE RELEASE PRODUCED BY ALPHA-METHYL-META-TYROSINE1962
- In‐Vivo Decarboxylation of α‐Methyl DOPA and α‐Methyl MetatyrosineActa Physiologica Scandinavica, 1962
- MODIFICATION OF EFFECT OF TYRAMINE BY VARIOUS AGENTS AND PROCEDURES1961
- NOREPINEPHRINE METABOLISM IN RAT BRAIN AND HEART1961
- The action of sympathomimetic amines in animals treated with reserpineThe Journal of Physiology, 1958