A Common B-Cell Precursor in Composite Lymphomas

Abstract
Bräuninger et al. (April 22 issue)1 identified a common germinal-center B-cell precursor for both Reed–Sternberg cells and non-Hodgkin's lymphoma cells in two patients with composite lymphoma. We studied five patients who had classic composite lymphoma with features of Hodgkin's disease and non-Hodgkin's lymphoma in the same lymph node to determine whether the two neoplasms were clonally related.

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