Synthesis of Methyl 3-Amino-3,4-Dideoxy-α and ß-D-Xylo-Hexopyranosides

Abstract
3-Azido-3-deoxy-D-glucose was used as starting material for the syntheses of methyl 3-amino-3,4-dideoxy- ß and α-D-xylo-hexopyranoside 9 and 15 and methyl 3-amino-4-chloro-3,4-dideoxy- ß and α-D-galactopyranoside 11 and 17. The ß-D-anomers 9 and 11 were stereoselectively obtained using Koenigs-Knorr conditions for the glycosidation step with the bromo derivative 3 as intermediate.