Abstract
During the microscopic examination of the brain of a patient who had died of purulent meningitis, I was surprised to find widespread lesions in the parenchyma of the central nervous system—an observation that I had not been led to expect from the current textbooks on the pathologic anatomy of the central nervous system. A study of a large amount of material and reference to the existing literature on the subject made it evident that by some strange omission the parenchymal lesions in purulent meningitis have been inadequately investigated and described. The purpose of this study is to draw attention to these lesions and their extent and nature and—what is even more necessary—to suggest explanations for their pathogenesis. Although this study deals only with purulent meningitis and the material is composed only of cases of this type, reference must also be made to tuberculous meningitis because of the overlapping of problems

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