Dynamic Regulation of the Endocannabinoid System: Implications for Analgesia
Open Access
- 1 January 2009
- journal article
- review article
- Published by SAGE Publications in Molecular Pain
- Vol. 5, 59
- https://doi.org/10.1186/1744-8069-5-59
Abstract
The analgesic effects of cannabinoids are well documented, but these are often limited by psychoactive side-effects. Recent studies indicate that the endocannab...Keywords
This publication has 144 references indexed in Scilit:
- Excitation of cutaneous C nociceptors by intraplantar administration of anandamideBrain Research, 2009
- Discovery and Characterization of a Highly Selective FAAH Inhibitor that Reduces Inflammatory PainChemistry & Biology, 2009
- Inhibition of fatty acid amide hydrolase produces PPAR‐α‐mediated analgesia in a rat model of inflammatory painBritish Journal of Pharmacology, 2008
- Enzymatic Pathways That Regulate Endocannabinoid Signaling in the Nervous SystemChemical Reviews, 2008
- Prostaglandin E2 glycerol ester, an endogenous COX‐2 metabolite of 2‐arachidonoylglycerol, induces hyperalgesia and modulates NFκB activityBritish Journal of Pharmacology, 2008
- Microglia produce and hydrolyze palmitoylethanolamideNeuropharmacology, 2008
- Multiple pathways involved in the biosynthesis of anandamideNeuropharmacology, 2007
- Synergistic antinociception by the cannabinoid receptor agonist anandamide and the PPAR-α receptor agonist GW7647European Journal of Pharmacology, 2007
- Site-specific increases in peripheral cannabinoid receptors and their endogenous ligands in a model of neuropathic painPain, 2006
- Inactivation of N-Acyl Phosphatidylethanolamine Phospholipase D Reveals Multiple Mechanisms for the Biosynthesis of EndocannabinoidsBiochemistry, 2006