Carcinogenic nitrogen compounds. Part LXXVII. A novel synthesis of β-carbolines

Abstract
N-Benzyl-3-piperidone phenylhydrazone undergoes Fischer indolisation at position 4, the cyclisation product being readily converted into β-carboline by palladium–charcoal; this represents a convenient new route to alkaloids of the harman group. Potentially carcinogenic angular benzo-β-carbolines have also been prepared in this way.
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