The licC Gene of Streptococcus pneumoniae Encodes a CTP:Phosphocholine Cytidylyltransferase

Open Access

15 August 2001

journal article
research article
Published by American Society for Microbiology in Journal of Bacteriology

Vol. 183 (16) , 4927-4931
https://doi.org/10.1128/jb.183.16.4927-4931.2001

Abstract

The licC gene product of Streptococcus pneumoniae was expressed and characterized. LicC is a nucleoside triphosphate transferase family member and possesses CTP:phosphocholine cytidylyltransferase activity. Phosphoethanolamine is a poor substrate. The LicC protein plays a role in the biosynthesis of the phosphocholine-derivatized cell wall constituents that are critical for cell separation and pathogenesis.

Keywords

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