Cloning of a Gene Encoding Bombyxin, an Insulin‐Like Brain Secretory Peptide of the Silkmoth Bombyx mori with Prothoracicotropic Activity
Open Access
- 1 February 1989
- journal article
- research article
- Published by Wiley in Development, Growth & Differentiation
- Vol. 31 (1) , 31-37
- https://doi.org/10.1111/j.1440-169x.1989.00031.x
Abstract
A genomic DNA encoding bombyxin, a 5kD brain peptide of the silkmoth Bornbyx mori with prothoracicotropic hormone activity, has been isolated. The nucleotide sequence coding for bombyxin shows high homology with insulin-gene family members and the overall organization of the preprobombyxin gene is the same as in preproinsulin genes, indicating that bombyxin shares a common ancestral molecule with insulin-family peptides. The bombyxin gene has no intron contrasting to other members of insulin-gene family.This publication has 46 references indexed in Scilit:
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